Wednesday, January 6, 2021

N1o1 Nitric Oxide Activating Anti-Aging Serum

Press Sample (Affiliate Links)

N1o1 Nitric Oxide Activating Anti-Aging Serum is the first anti-aging skincare to use a Nobel Prize winning scientific discovery to defy the effects of aging skin, "by correcting the cause of wrinkled and damaged skin. N1o1 stimulates collagen production and restores the youthful flow of oxygen, hydration, and nutrients to your skin cells." 

This dual chamber serum, which is clinically tested, cruelty-free and fragrance free, features two serums that are used together. You simply use a pump from each chamber, mix them in your hands and apply them to your skin, and by mixing them together the Nitric Oxide is activated for maximum efficacy. Do not be alarmed that the Nitric Oxide can cause your skin to become a bit flushed, pink and warm. I do notice a slight pinkness to my skin when I first apply it, but it doesn't last too long.

This serum stimulates collagen production and simultaneously helps oxygenate and hydrate your skin cells. As the body ages it produces less Nitric Oxide, and the result is that wrinkles appear, skin becomes less taut and age spots begin to appear. Therefore, this serum is formulated to improve the appearance of lines and wrinkles and it helps diminish hyperpigmentation.

While I do not have wrinkles, I do have a few fine expression lines, and a small area of sun damage, and after using this serum for about a month I noticed that the fine lines were less noticeable and that the sun spots have faded.

According to N1o1,

N1o1 is a revolutionary breakthrough in the science of age-defiance that will change the way you look and feel forever!

N1o1 Nitric Oxide Activating Serum is the FIRST anti-aging skincare that uses a Nobel Prize-winning discovery to defy aging skin by correcting the cause of wrinkled and damaged skin. N1o1 stimulates collagen production and restores the youthful flow of oxygen, hydration, and nutrients to your skin cells.

The problem is our body makes less Nitric Oxide as we get older. This is the reason your skin AGES. N1o1 restores the missing N.O. to get to the root cause of aging skin. The result: wrinkles and dark spots disappear, tone improves and you’ll love the way your skin looks and feels.

How to use:

Proactive Skincare Starts In Your 20s: Apply 1 time daily before the appearance of lines. Use one time daily in your 20s before the fine lines and wrinkles form. Make N1o1 part of a daily proactive skincare routine, before the signs of aging appear.

Rejuvenating Skincare (1 – 2 times daily): By age 40 your body produces only 50% of what it needs to keep your skin from aging and 15% by age 65. Most people already show the appearance of fine lines and wrinkles. Use N1o1 Nitric Oxide once or twice daily, depending on the aging and the condition of your skin. N1o1 may slow the progression of the appearance of fine lines and wrinkles and improve your skin’s clarity, tone, and texture.

Restorative Skincare (2 times daily): Dermatologists, plastic surgeons, and skincare professionals recommend and use Pneuma for their patients. Use N1o1 Nitric Oxide twice daily on aged, blemished, or damaged skin.

Recommendations and What to Expect:

N1o1 is the first multi-generational skincare. It is recommended to use this product in the AM and PM on clean skin. Dispense a single pump from each chamber. Mix together and apply to face and neck. When serums from the dual chambers are mixed together, the nitric oxide is activated. As a result of the nitric oxide activation, certain skin types could show a pink tone lasting a few minutes. Allow serum to fully absorb 1-2 minutes before applying or continuing with your normal daily skincare regime. At 30 ml. there are 60 applications in each bottle.

N1o1 can be used as a stand-alone skin treatment or as a primer for your existing skincare regimen. N1o1 prepares your skin to make any skincare treatment work better. Our unique formula is designed to optimize absorption in the skin and improve the look of fine lines, wrinkles, and discoloration. N1o1 synergistic Nitric Oxide dual-chamber delivery system also contains a high-concentration of powerful antioxidants proven in peer-review studies to help prevent the free radical damage that can lead to the appearance of premature aging. Because we don’t use any chemical preservatives that can permeate into your skin, our all-natural antioxidants may develop a slight amber hue. This is perfectly normal, does not affect N1o1 effectiveness, and let’s you know N1o1 contains only the healthiest ingredients.

The benefits of N1o1 Nitric Oxide Activating Serum are the improvement in overall tone, texture, and clarity of the skin and will soften the signs of aging.

Directions: Apply a single pump from each chamber to the palm of your hand, mix together and apply to the entire face and neck. Allow to fully absorb 1-2 minutes before applying anything else. Continue as a daily routine, applying morning and night to a clean face. NOTE: Within a few seconds your face may turn a slight pink due to an increase in nitric oxide. This may last up to 5 minutes.

IngredientsWater, Ascorbic Acid, Polysorbate 20, Hydroxyethylcellulose, Sodium Nitrite, D-Tocopheryl Acetate, Dehydroacetic Acid, Benzyl Alcohol, Sodium Sulfite, Sodium Metabisulfite, Tetrasodium EDTA.

Overall Assessment: This is definitely a luxury skincare product, but it actually works, and seeing a measurable difference makes this a worthwhile purchase.

$180.00 for 1 oz. from N1o1 and Amazon (Affiliate Links).

Press Sample. All views expressed are categorically my own. Copyright © 2021 All Rights Reserved.


  1. I love this serum. I've been using it and will cry when it's empty. Mixing the two serums together is a great way to produce the efficacy of the skincare.

    1. I completely understand why you love this serum so much, Marcia!

  2. Oh this sounds amazing, I wish it wasn't so expensive.

  3. I love double-sided skincare products like this. If I could afford it, I would try it in a heartbeat.

    1. Me too, and this one is not only a pleasure to use, but the serums are quite effective!

  4. That is such a cool bottle design!

    1. It really is, and it is so easy to use, Anastasia.


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